Semaglutide for Bodybuilding: Is It Good for Cutting?



As a aggressive bodybuilder, you’ve gotten a tremendously troublesome job main as much as a contest. You must current a physique with most muscle and minimal fats. You undertake a strict reducing course of within the weeks main as much as present day to attain the specified ripped mass look. You may take any benefit you may get that is protected and authorized, proper?

So what about Semaglutide? As you are little doubt conscious, this GLP-1 receptor agonist, as present in Ozempic and Wegovy weight reduction medicines, is essentially the most popular weight loss medication on the planet. However is it any good for bodybuilders reducing for a contest?

On this article, we go on to the supply to seek out out. Learn on for actual experiences, actual recommendation, questions, and solutions from bodybuilders who’ve been and are utilizing weight reduction medicine containing semaglutide to get shredded for competitors day whereas sustaining lean muscle mass.

This text will cowl:

  • Actual Bodybuilder Experiences with Semaglutide
  • What’s Semaglutide?
  • What Sort of Bodybuilder Will Profit From Semaglutide?
  • How Can Bodybuilders Get Semaglutide Prescribed?
  • Is Semaglutide Value The Price?
  • Can Bodybuilders Get Semaglutide Lined By Insurance coverage?
  • Semaglutide Dosages
  • Semaglutide Aspect Results
  • Different FAQs
  • Wrap Up

Actual Bodybuilder Experiences with Semaglutide

There are some very energetic semaglutide and bodybuilding discussions on such platforms as Reddit and bodybuilding boards. I’ve spent a number of hours studying these feedback to get a basic taste of individuals’s experiences with the compound.

Case Research

One bodybuilder tracked his weekly expertise with semaglutide injections. This man’s beginning weight was 240 kilos, and his objective weight was 215. He went to a clinic as soon as per week and was given a .25 mg injection of Ozempic.

Along with a weekly semaglutide injection, this man was taking the next dietary supplements: Males’s multivitamin 10-15 grams of fiber a day (psyllium husk), Whey protein isolate, Fish oil, Vitamin D3, CoQ10, Zinc, Magnesium.

He was additionally on the next Anabolic steroids: Testosterone propionate: 350mgs per week, Nandrolone Phenylpropionate: 350mgs per week, Winstrol: 50mgs/day.

At a .25 mg weekly dose, he was feeling the urge for food suppression results for the primary three days, however then they wore off, and his starvation cravings returned. After a few weeks, he determined, in session together with his physician, to extend the dosage to .5 mg. The .25 mg injections didn’t give him any unwanted side effects.

The day after upping the dosage, he had misplaced three kilos. Twenty days after starting his semaglutide injections, he had misplaced a complete of 10 kilos, which was greater than he had anticipated.

When questioned as as to if the burden loss is likely to be partly because of lack of muscle, the OP wrote:

My fasted weight is 234.7lbs. I began at 244lbs so I’m down virtually 10lbs in 20 days.

That is fairly aggressive and greater than I anticipated. Some might say it’s muscle loss- it isn’t. I do know it isn’t as a result of I devour 225-250 grams of protein a day, plus I’m utilizing anabolic steroids to protect muscle mass.

I’m persevering with to maintain my weight loss program dialed right into a T and I do know precisely how a lot I’m consuming each day.

I’m attributing the large weight reduction outcomes to the weight loss program, 30-40 minutes of cardio 5x per week, and weights 5x per week.

I’ll most likely solely use this for an additional 2-3 weeks to drop one other 7-10lbs. At that time it will likely be time to let my physique relaxation, get blood work finished, and put together for my low season and pack on one other 20-25lbs to shoot for muscle progress.


After three weeks at a dosage of .5 mg, the dosage was elevated to .75 mg per week. He achieved his 15-pound weight reduction objective and didn’t expertise any vital unwanted side effects.

What’s Semaglutide?

semaglutide for bodybuilders

Semaglutide is a sort of brief chain of amino acid often called a peptide. It falls inside a classification of peptides often called a GLP-1 receptor agonist. These peptides mimic the consequences of a hormone known as GLP-1, which the physique releases into the intestine after consuming. It makes you are feeling full, however solely lasts for a few minutes.

By making alterations on the molecular stage, scientists have been capable of lengthen the half-life of the peptide. Consequently, whenever you take semaglutide, you are feeling fuller for longer after consuming. That is as a result of it slows gastric emptying by lowering the pace with which meals strikes by the intestinal tract.

Semaglutide additionally impacts leptin sensitivity. Leptin is a hormone produced by the mind whenever you eat. It alerts that you’re now not hungry. It seems that semaglutide will increase leptin receptor sensitivity. This contributed to the sensation of not being hungry.

A 3rd means that semaglutide helps you shed extra pounds is by selling further insulin secretion from the pancreas. It additionally prevents the liver from releasing extra quantities of glucose. This helps to cut back the chance of glucose being saved as extra fats. It additionally lowers blood sugar ranges.

A 2020 Step 1 Trial, revealed within the New England Journal of Medication, confirmed vital weight reduction leads to contributors with persistent weight administration wants. 1961 overweight individuals got 2.4 mg of semaglutide or a placebo for 68 weeks.

The semaglutide group misplaced a mean of 14.9% of their physique weight, in contrast with 2.4% for the placebo group.¹

There have been different GLP-1 receptor agonists. The factor that has set Semaglutide half is that, relatively than requiring day by day injections, it solely must be taken as soon as weekly. That makes it way more accessible and acceptable for many individuals, resulting in the worldwide Ozempic frenzy.

The underside line is {that a} Semaglutide weight reduction drug helps you are feeling fuller for longer after consuming a meal. Consequently, you’re more likely to devour fewer energy, resulting in significant weight loss, particularly when mixed with a wholesome way of life.

What Sort of Bodybuilder Will Profit from Semaglutide?

semaglutide for cutting bodybuilding

The principle good thing about taking semaglutide is that it’s going to stop you from dishonest in your weight loss program and snacking between meals. In case you occur to have iron willpower who would relatively dive into shark-infested waters than cheat in your weight loss program, then you do not want semaglutide.

Nonetheless, when you occur to be like most mere mortals and end up tempted past restraint in these days and weeks main as much as competitors day, semaglutide could possibly be the answer to holding on monitor.

As a private coach who works with aggressive bodybuilders, I’ve seen guys who turn out to be obsessive about meals over the last couple of weeks of their reducing section. All they consider is having the ability to swap their hen and rice for ice cream and donuts. Inevitably, they find yourself dishonest.

I’ve additionally seen firsthand how taking Ozempic can flip that script. Immediately, these identical individuals are now not food-obsessed. They’re capable of eat their scheduled lower meals and go on with their day, not even enthusiastic about snacking or taking in unscheduled energy.

However I’ve additionally seen the unwanted side effects of that benefit. These embrace nausea, diarrhea, and abdomen ache. That is not what you need to be coping with whenever you’re peaking for a contest.

How Can Bodybuilders Get Semaglutide Prescribed?

ozempic for body builders

In case you’re a bodybuilder who has determined to take semaglutide throughout your reducing cycle, you might want to make an appointment to see a medical skilled. As imposed by the FDA, the standards are to have a physique mass index of 27 or larger together with a weight-related well being concern. This could possibly be elevated blood stress or excessive LDL ldl cholesterol.

Alternatively, you could possibly have a BMI of 30 or larger with no related weight-related medical situation.

The medical skilled will totally assess your medical historical past and contemplate every other medicines you take which will work together with semaglutide. She or he will even talk about your consuming habits and way of life to make sure that you’re doing all the things you might want to do to advertise wholesome weight reduction naturally.

If he’s glad that you just meet the standards for semaglutide for weight reduction, the physician will prescribe a course of remedy for you. It will contain once-weekly injections, which may be finished at residence. You’ll sometimes begin with a dosage of 0.25 mg per week. Your physician will monitor your outcomes, week to week, and will improve the dosage if you’re not reducing weight.

Is Semaglutide Well worth the Price?

semaglutide dosage bodybuilding

Semaglutide, whether or not within the type of Ozempic or Wegovy, is dear. In case you are lucky, it is possible for you to to assert a big proportion of that price in your insurance coverage. In any other case, you’ll be forking over a hunk of cash every month.

The precise value varies based on the precise drug and producer. Listed here are a few typical experiences from Reddit customers:

Sup guys, went to my doc and obtained it for weight problems (lol BMI occurred to be 30 on the dot (6’1 230) trigger I used to be on the finish of the majority, my combating weight is about 200.

He subscribed me an ozempic pen and it was 25 bucks after insurance coverage. (This prices actually $1300 within the US with out ins). Been injecting .25 per week and it’s working OK. Nausea is annoying, however I’m hoping that subsides.

u/Environmental Rule 525

I undoubtedly need to preserve operating this after I end my vial however at ~$1000 for 10mg from Empower Compounding Pharmacy (Marek‘s supply) it’s simply an excessive amount of, as a result of the minimal efficient dose for me at 1mg/week can be $100. I haven’t discovered a less expensive supply but so extra updates to return.

u/Twiggy Sawdust


The query you must ask your self is, ‘Am I ready to pay within the neighborhood of $300 per week for an appetite-suppressing drug?’ After all, whether or not you possibly can afford to is one other query solely.

Can Bodybuilders Get Semaglutide Lined by Insurance coverage?

Ozempic, Wegovy, and different semaglutide-based prescription medicines are being prescribed for weight reduction if the affected person is clinically overweight. It’s as much as every insurance coverage firm to resolve as as to if they’ll cowl these medicines.

To be prescribed for these medicine within the first place, bodybuilders will have to be labeled as being ‘overweight.’ That is not that troublesome. The utterly irrelevant weight problems scale (BMI) doesn’t take into physique composition. Consequently, a bodybuilder with an honest quantity of muscle mass might be labeled as overweight, regardless of having decrease physique fats ranges than 99% of the inhabitants.

Semaglutide Dosage for Bodybuilders

semaglutide bodybuilding dose

Semaglutide dosage schedules contain regularly growing the injection to present the physique time to get used to it. There are normal dosage protocols for Ozempic and Wegovy, the most well-liked types of taking the drug.

Here is a chart displaying the everyday dosing schedules for each medicines:

Week # Wegovy Dosage Ozempic Dosage
1-4 0.25 mg 0.25 mg
5-8 0.5 mg 0.5 mg
9-12 1.0 mg 1.0 mg
13-16 1.7 mg 1.0 mg
17+ 2.4 mg 1.0 mg

So, how does this examine to the quantities that bodybuilders are taking?

There’s fairly a bit of dialogue relating to dosing protocols on the Extra Plates Extra Dates Reddit thread. Most bodybuilders appear to start with a .25 mg dosage. That is taken as soon as weekly by injection. Nonetheless, fairly a couple of individuals have commented that the urge for food suppression impact wears off after two or three days. Consequently, they elevated the dosage to .5 mg per week.

Some individuals have needed to improve the dosage to 1 mg for the fullness impact to final for the complete week. Right here is one person’s expertise:

After a couple of days on the primary week the efficiency of .25mg/week rapidly wore off, and the next week I virtually barely felt it. I upped it to .5mg, and the impact was additionally minimal, lasting possibly a couple of days. This week I went as much as 1mg and now I can really feel the urge for food suppression final for the entire week.


It is attention-grabbing to notice that Derek from Extra Plates Extra Dates personally makes use of a 2 mg dosage. This didn’t produce any untoward unwanted side effects, although the long-term results are unknown. That is the dosage he must have the urge for food suppression impact final for the complete seven days till the subsequent injection.

It must be famous that the dosage used within the Step 1 Trial referred to earlier was 2.4 mg, taken as a once-weekly injection. Nausea and diarrhea have been the primary unwanted side effects, although, for many examine contributors, these went away after two to a few weeks.

Remember, too, you could’t arbitrarily resolve on the semaglutide dosage you’ll take. It is a prescribed remedy. So, the dosage quantity is a call that’s made in collaboration with the medical skilled who prescribed the drug to you.

What Aspect Results Have Been Reported?

glp-1 bodybuilding

Not everybody who takes semaglutide will expertise side effects. My casual evaluation reveals that about half of commenters on Reddit haven’t any antagonistic results when taking the drug. The opposite half report nausea, diarrhea, abdomen ache, and elevated coronary heart charge as the most typical unfavorable reactions.

Here is a sampling of feedback from bodybuilders who’ve been taking semaglutide throughout their reducing section:

I additionally battle with train induced nausea. I preserve my coronary heart charge decrease, don’t get on my Peloton as a lot and go quite a bit slower on hikes. If I get close to 170 I get very nauseated and lightweight headed, typically have to take a seat down till it passes. I haven’t pushed it to the purpose of puking. I’ve maintained lifting 3x week however go slower and never as many bursts to maintain my coronary heart charge a bit decrease. I don’t assume I’ve sacrificed any muscle mass however I’m additionally don’t thunk I’m constructing extra. Comfortable with that as I spent the yr previous to semaglutide targeted on energy relatively then cardio and am in a energy place I’m general proud of.


Good luck with the exercise-induced nausea. I genuinely imply it; it was a ache within the ass for me. It took twice as lengthy for me to get my exercises in. I did discover although with extra water consumption it wasn’t as unhealthy; nonetheless, it was nonetheless current.


Be careful for the unwanted side effects, they suck. I had complications for the primary month or so and nausea, and that was on low dose (.25mg)- i’m simply now on 1mg (truly .75 as i’m simply going up 10 ticks on slin pin each few weeks to get to larger dose slowly). Def works quick with urge for food suppression initially however i discovered that you just get used to it and that i are inclined to eat extra.. however nonetheless reducing weight and garments match higher.


From the above feedback, we see that these unwanted side effects have been skilled at dosage ranges starting from a low of .25 to a excessive of 1 mg. The reactions appear to be extremely particular person dependant. Simply because one individual experiences nausea and complications doesn’t suggest that you’ll. The one method to discover out is to present it a trial.

Different FAQs

Can I construct muscle mass with semaglutide?

Semaglutide just isn’t a muscle-building drug, so no, it won’t assist you construct muscle. Relatively, it’ll assist you to remain true to your reducing weight loss program by holding you full. It will assist you to withstand the inevitable temptations to interrupt your weight loss program that occur within the days and weeks main as much as a bodybuilding competitors.

Will semaglutide affect my exercise means?

Whether or not or not semaglutide impacts your exercise is determined by how your physique responds to the remedy. Some bodybuilders will expertise nausea, complications, and basic malaise throughout the first few weeks of remedy. This might nicely have an effect on the flexibility to work out. Others won’t expertise any unwanted side effects. In actual fact, they won’t be as food-obsessed throughout the ultimate weeks of contest prep, permitting them to focus extra totally on their exercises.

Are you able to get ripped on semaglutide?

Semaglutide may help you to get ripped by staying strict to your reducing weight loss program. It is going to preserve you full between meals, making you far much less more likely to cheat in your weight loss program.

Is it protected to take anabolic steroids with semaglutide?

Some sorts of steroids might negatively work together with semaglutide. For instance, Prednisone (a corticosteroid relatively than an anabolic steroid) might negatively have an effect on semaglutide’s means to control blood glucose ranges. In case you are taking steroids in addition to semaglutide, you need to frequently have your blood sugar ranges checked.

ozempic and bodybuilding

Wrap Up

Semaglutide just isn’t a “magic” reducing formulation for bodybuilders. Its key profit lies in its means to maintain you feeling full between meals, making you much less more likely to cheat in your weight loss program. In case you’re a type of uncommon people whose dedication to eat clear would not want any boosting, you do not want it. Nonetheless, when you’re like most bodybuilders who battle with their weight loss program main as much as competitors, semaglutide can undoubtedly assist you keep on monitor.

In case you are interested by pursuing a prescription for semaglutide, however aren’t positive about the very best place to get it, you possibly can learn our article on Where to Buy Semaglutide.

In case you’re a bodybuilder who’s been taking semaglutide throughout your reducing cycle, we might love to listen to the way it’s been going for you. Share your expertise within the feedback beneath.


  1. Wilding, John P. H., et al. “As soon as-Weekly Semaglutide in Adults with Chubby or Weight problems.” The New England Journal of Medication, vol. 384, no. 11, 10 Feb. 2021, pp. 989–1002,,


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